Perhaps I don’t comprehend all that has been stated but it seems that the sweet spot velocity is being chased in favour of the results on paper.
The basic objective of the Ladder Test is to identify a range of velocities which have minimal to zero vertical impact. Nothing more. You can use powder weight instead of velocity, but it blunts the tool, as the same powder weight will give different velocities. The idea of the Ladder Test is to establish a target velocity for further testing. It is not the end of the road. You are using the paper to tell you what velocity works and what does not.
The OCW method I would describe as more of an organized blind trial and error method. If you are going to simply do trial and error as many shooters do, it is good to be organized so you don't go in circles. The OCW is as good a way to organize as any. I just don't think there is anything magic about it. It is basically, shoot lots of groups and decide which ones you like.
Aside from velocity, there are some general things you can do to make your load more "tolerant":
Powder - This is your basic control of velocity. You generally want the slowest powder that achieves your sweet spot velocity. Ideally you want the case close to full, full, or somewhat compressed.
Hodgdon Extreme powders are very temperature insensitive. Many think that means they don't change velocity when the ambient temperature changes. But, there is more to it than that. Your cartridge "cooks" in the chamber while it sits there waiting for you to get organized and get the shot off. You can get erratic pressures and velocities if your cooking time of a temperature sensitive powder is erratic. See the link below for some interesting data. Of the top 100 shooters surveyed they all used Hodgdon Extreme powders!
Bullets - They can have one of the largest effects on accuracy. You need to find bullets that agree with your barrel twist, and throat dimensions. And there have been developments in the design of bullets to make them more tolerant to seating depth. Yes, you still need to shoot to determine the best depth, but they give you more tolerance, kind of like finding the velocity tolerance band. If you look at the survey at the link below, you will find that the
Berger Hybrid bullet which has been designed to be seating depth tolerant is the most popular.
Primers - They are probably the biggest mystery of the consumable reloading components. A fellow in the US, by the name of German Salazar did some extensive testing and used to have a public blog with the full results. He has now made it a private blog, but you can find a few photos of the
results of his testing here. The problem seems to be that there is no general consensus as to whether you want a big bang primer or a small bang primer. There are proponents of both schools of thought. However based on the same survey below CCI seems to dominate the choice of pros, with the exception of the Federal 210M in large rifle. And of course measuring velocity ES and SD can help with the selection of primers that are best for your powder and cartridge.
Reloading Components - What the Pros Use
So, I guess my point is that I find getting to the best load is done by looking at each issue independently and selecting the most tolerant velocity, bullets, and powder. Good groups will follow. You have to have some faith!