Lots of good info!
I have AI'd a few cases. I also pretty much red line the pressure in every rifle I reload for. It appears that your cautionary comments about pressures say that you do the opposite. Pressure from a loading manual causes me about as much concern as COAL from a loading manual. I'm not disagreeing with what you are saying, in principle, but every rifle is different, as is every reloader's tolerance for, well, tolerances.
A very tight chambered 243 was once had, with a barrel manufactured from a local smith. It hid pressures very well, and produced significant speeds. I know the pressure was high, as there is no free lunch for velocity, but none of the "typical" symptoms were there. It caused me no concern. No one died, the rifle didn't blow up, no lugs were sheared off, and so on.
Hand over a 260, loaded with book loads, and an AI reamer for same, and then wager the whole works that a 100fps gain wouldn't happen, using typical "reloader" pressure judgement techniques? Dreams would become reality.
There are more powders available than ever before, along with some of the best quality brass an primers ever manufactured, to say that something isn't possible after so many have done it, without knowing the all of the circumstances, IMO, shouldn't be done.
Many respect your experience and opinions based on same here, including myself, and after glancing at your post count, and seeing how many posts you've made on this thread alone, it's obviously something you feel strongly about.
To be clear, I am pro AI, in certain cases, for certain expected and known results. I agree 100% that it isn't for everyone.
R.