I have about four moulds that are without lube grooves.
While I haven't done any empirical tests, I think that the powder flows a bit during cooking, and any smearing done by the pliers is moderated a bit.
When using coloured powders, I noticed that some bullets that had a noticeable scuff from the pliers before cooking, looked fuller after. That was the pigment that I saw. The clear part of the powder could be more intact.
Nowadays I only use the clear powders for rifle bullets, and all the rifle bullets I've shot in the past year have been without lube grooves.
I have had excellent results with them.
I have found that it's easier to cast good bullets in moulds that have no lube grooves.
With Accurate Molds, you can specify the diameter of the as cast bullet, with the alloy you specify. They are usually spot on.
While Accurate Molds are expensive, their bullets are accurate, and the turn around time, in my case, has been two weeks or less.