One of the 4350's is a great choice in the 30-06 up to 165/168 grains. Above that some benefits can be gained with IMR 4831, RL 22, Vihtavuori N165, and AA3100. My pet load with the 165 TSX is 60 grains of Vihtavuori N160. 2900+ in my 24" barrel and sub MOA. Work up carefully. This is a max working load in my rifle. Regards, Eagleye.