There is a 17 HMR semi that utilizes the ruger 1022 afteraftermarket parts.
So a SR 22 chambered in 17 HMR is possible
Im pretty sure that it's a no no,simply because i think,and i say I THINK,that the 17 hmr should have a bigger receiver just like the 10-22 in 22 mag,so it wont fit in a SR 22 chassis.