You are referring to Hodgdon H4198 powder right?
Modern Reloading by LEE circa 1996 shows a 500 grain bullet behind 25.2 - 28.0 of H4198 for 1082 fps.
Hodgdon’s 2019 Annual Reloading manual shows a 500 grain Lyman # 457125 bullet behind 42.0 grains of H4198 @ 1523 fps, to 46.6 grains of H4198 @ 1650.
Bet that last load would be a flinch-inducing shoulder buster.