Is the ammo shown below the Winchester .22LR 45 grain Subsonic ammunition in question?
If this is the same ammo, it's ballistic coefficient is .141, as provided by the manufacturer. It doesn't appear to have a BC significantly better than some 40 grain standard velocity ammo.
Equally or even more important than wind drift when shooting .22LR at long distances, is vertical spread caused by muzzle velocity variation. Match quality ammo will have a smaller ES than any currently produced Winchester .22LR ammo. For standard velocity ammo, each 10 fps velocity difference between rounds causes .25" of drop at 100 yards. At 200 it's about 1", about 2.4" at 300. To illustrate, a 40 fps velocity difference between two rounds, the vertical spread at 100 would be 1"; at 200 it would be 4" and at 300 about 9.6".
While wind drift is an important consideration, ballistics calculations indicate that the Winchester 45gr ammo drifts more in the wind than something like SK or Lapua standard velocity rifle ammo, which has a BC of .161.
Winchester .22LR 45gr ammo will drift .49" for every 1 mph of crosswind. For each 1 mph it drifts 1.71" at 200 and 3.58" at 300 yards.
SK or Lapua 40gr ammo will drift .44" for every 1 mph of crosswind. For each 1 mph they drift 1.50" at 200 and 3.15" at 300 yards.
For a 10 mph crosswind, multiply each figure by ten. To illustrate, at 200 yards the 45gr round would drift about 35.8" and the SK/Lapua round would drift 31.5" -- a difference of about four inches less for the SK/Lapua.
For the Winchester 45 gr chart, see http://www.shooterscalculator.com/ballistic-trajectory-chart.php?t=ef27c069
For SK/Lapua 40gr chart, see http://www.shooterscalculator.com/ballistic-trajectory-chart.php?t=2560bbe7
The bottom line is that this Winchester .22LR 45gr ammo is not likely to perform better at long range than other available ammo.
Below are the charts linked above, showing wind drift for the Winchester 45gr ammo first, the SK/Lapua beneath.
