I will take a shot that is 300 + yds if there is no choice. The furthest I have shot was 752 m. Now before you start throwing rocks... I laser every animal over 200 m. I shoot from a bi-pod whether prone or sitting. I won't take the shot unless I am sure of the set up and confident that I can. I carry my "up's" on a laminated card, and adjust my scope to the target distance. I fire custom rifles that I handload with the same dedication and precision as my competition guns. I shoot these rifles frequently at extended distances. I compete in F class matches, on a busy year I will fire 2000+ rounds (all in rifle). Wind reading is the other big thing when playing at the extended ranges, and the only way to get good at this is to put a lot of lead down range. I use a 338 Lapua and a 300 WSM for my long range hunting. I don"t go looking for the shot but in some places that I hunt in there is no cover and no chance of getting closer to the animal. In the 23 years since I started hunting the vast majority of the animals taken have been under 150 m, but I feel confident in my skills as a shooter that if presented with the "long" shot I have the ability to make it. Now I don't suggest that the average hunter who makes a box of shells last 3 years set out to do this but if you practise and use the right tools the ability to make the shot is there.
This is my opinin only. Don.