For the 10% of us that are left handed, I actually don't mind shooting semi-auto right handed guns. It's all in the practice. I've got a Spetnaz video on how they train with the AK and for right handed use, they actually reach around underneath the gun and chamber rounds with their left index finger so they never take their finger off of the trigger. I grew up running right handed bolt guns while using my dominent eye and became quite fluent at it. Now that I have a left handed bolt gun, I wouldn't trade it for the world so maybe assault rifles would be the same. I've never held one unfortunately.