I use a Bushnell 1x28 red dot on my 10/22, it's been working great so far. The only cons are the small objective diameter and slight dark tinge to the optics. I find myself using Tech-Sights much more often however as I really enjoy the sight picture and fast alignment.
Don't buy the super cheap-o scopes, even for a 22. I've destroyed a couple of gun show specials in fairly short order with what I thought would be low or moderate recoiling calibre guns (9mm, 223, 22 WMR, 30-30 Win). On the other hand, I've put the Bushnell on a .270 bolt action for fun and it's held up just fine (not that I recommend it!).