I had many discussions with folks when I was deciding which cartridge to use in a 6.5mm rifle I was building. I ended up with the 260 Remington for the following reasons:
1. Brass is easily available, without any fire forming. Now that Lapua makes brass, the
quality of brass is even better.
2. Using Winchester 7mm-08 brass necked down to 6.5mm, I get 2940 fps out of a 27 inch Obermeyer barrel with a 140 grain Sierra bullet.
3. The improved rounds, like the mystic, or 6.5-08 Ackley improved, will get me only about another 150-200 meters of usable distance. The 260 bullet I'm using doesn't go transonic until around 1500 meters. I rarely shoot over 1500 meters, so all the extra work of fire forming brass to get another 200 meters would be lots of work for something that is rarely (if ever) used.
4. I couldn't justify the reduction in barrel life for extra distance that I don't even use. I have had the new 260 Rifle for about a year so far, and the greatest distance I have shot it was 1425 meters.
I figured it just wasn't worth the extra time and effort to fire form brass, just so I could get another 200 meters of distance that I don't use. And, all the extra work, shortening barrel life, extra powder cost, just wasn't necessary. In hindsight, I made the right decision.
However, I love to tinker with things, so I understand the entertainment value of doing things like getting the hottest cartridge you can, just to do it. It would be interesting to have a 300 RUM cartridge necked down to 6.5mm, but the barrel life would probably only be around 800 rounds...and I can't figure out what I would need it to do other than launch a 143 grain bullet at around 3500FPS.