Seems like the old standby argument. Which bullet will kill such and such better. Well, so far, everyone is missing the basics.
1) Practice with a round for a good while beforehand at the range. Don't expect to sit on you arse all year, grab the rifle and go to hunt camp and be all that and a bag of crisps.
2) Sight your darned rifle in. Goes well with #1. After practicing at the range all year, you will know your rifle and optics. You can change up for the new round a month or so beforehand and get out to sight the rifle back in and go back to #1.
3) Once you have practiced, sighted in your rifle to the round you are hunting with. Now the day has come. The morning breaks and there, coming into the open is a NICE bull moose. You raise your rifle and blast away, emptying your mag. More than likely missing completely or just wounding the animal. How about taking your time, execute the plan for every shot, and make EVERY shot a kill shot?
I am also an archery hunter and we know that there is one chance to make that shot into the vitals/kill zone. I never understood why some gun hunters are so ignorant as to just blast away at something without even starting at the basics. Gun is away for 11 1/2 months of the year or more. Might stop by CT for a new box of ammo. Probably not the same stuff used before and different bullet weight. Never bother to sight in or practice. Sighting in and practice are to be done beforehand at the range. Not when you get to camp unless you are hunting about 20+ miles away from your camp location. Since everyone showing up and blasting away does spook the animals from that area.