I used to, but when the average shot was around 100 meters it seemed like overkill. I also nicknamed it "The Car Axel" because of the weight.
I now use a Tikka T3 SS that's about 4-5 lbs lighter than my heavy bbl Remington and more than accurate enough with hunting ammo. (MOA at 100 meters)
I think I enjoy hunting much more with the lighter rifle and can certainly go longer and harder but "hey" whatever turns your crank. If you don't mind lugging it, than more power to you.