I can give my opinion and observations from what I have and what I have shot.
Uberti: Buddy has one in 45 Colt. It is a nice gun and functions like a standard Colt would. I was not enamored with it, but I like the shiny nickel type finish and it was case hardened.
Beretta: Another shooting buddy has 2 of the Stampedes; one in 45 and on in 357. It has been a while since I shot them, so I do not remember if they have the clicks to the hammer ####, but they do have a transfer bar safety and, therefor, are safer to carry with six rounds if you so decide. A standard SAA leaves the firing pin sitting on the sixth round`s primer if you load it full and put the hammer down; that does not happen with a gun with a transfer bar type safety. That does not really concern me as I always load one, leave an empty chamber, load 4, and then bring the hammer all the way back and then down on whatever I use. My buddy loaves his 357, but hates the 45; he has nothing but problems with it. In saying that, he sold the 45 and bought a Blackhawk with a 45 Colt and 45 ACP cylinders.
Ruger: I have the most experience with these. I owned a stainless New Vaquero with a 4.62`barrel in 357. Go to my previous statements about the safety system for the Beretta as they are similar. There is no click of the hammer on these, but I am not as much of a traditionalist so it doe not bother me. The cylinder would not reverse index; it did not bother me, but could be an issue if you were shooting a CAS match. That being said, someone else may want to chime in if he others have the ability to reverse index. It was accurate and pretty with the polished stainless finish. It handled recoil better than my S&W 27 with 357 loads as it rolled in the hand instead of hammering straight back; it is not as quick back on target, but it is not as punishing with those hot Remington UMC loads we found. I no longer have it for two reasons: I always have my eye out for the next best thing, and my buddy wanted it and accepted what I wanted for it. I sold it to him and bought a New Vaquero Bisley in 357. I find the Bisley points better and balances better with the longer barrel (5.5"). The downside is that the trigger is at 7lbs, the hammer spring is wicked stiff, and it does not roll the same with the 357 loads. That being said, I find it more accurate and the trigger can be fixed quite easy by Jason Spence here in Ottawa. The difference in recoil dissipation is negligible and I shoot little 357 out of them anyways.
Here are my opinions and observations; I hope they help.