I recommend the Dillon 550. This is a one time purchase press that will last you a lifetime. I bought mine in 1990 and is loaded well over 400,000 rounds, I presently measure handgun rounds in gallons on hand. At one point I broke a a plastic powder throw canister when I dropped it on the cement floor about 5 years ago. I called them and said I had a problem and their reply was "no you don't"! They asked me my phone number and I had to remember it from back in 1990 and they said, what I can we do for you Mr. _______, they then asked for my present address and updated the phone number. They replied that the part was in the mail. I then asked if I could add a pin that holds the block in place which I had misplaced over one of my moves. They said, that has been added. I asked what the cost would be and they said nothing, it is looked after, shipping included.
I have since been to Dillon in Phoenix just to check the place out and said one of the plastic pieces on the electric case feeder was a little faded over the years and they got one from the back and once again no charge. I picked up a 550 also that day and brought it back for a friend. The disadvantage of buying the press though directly at Dillon is you have to pay the State sales tax. If you have it shipped to a US postal address it was free shipping and no sales tax. The guy I brought it back for did not have a US postal account so he did not care about the US tax.
I presently own two 550s, one with an electric case feed. A 650 may be in the near future.
Advantages of 550:
Will load just about anything (rifle and handgun). Very rugged, easy to setup and use for anyone that has reloading experience. You can add on an electric casefeeder at any time. You can sell it at any time for just about what you paid for it. Customer service that can be a model for any business. Was free shipping to US address, would have to check now. Dies are excellent. You can add a power case trimmer for rifle at a later date (I have one and it works great). I have a friend who purchased a 650 as his first progressive press and he did fight with it a little at first during the learning period but he openly admits that he is a little on the non mechanical apptitude side, the auto indexing is nice but I have done with out it so far and have loaded lots of rounds. These though can be expensive intially.
Ad for loads for .45, do not want to suggest any but it is a very forgiving catridge. I have use bullseye, 231 and clays depending on bullet and application. See Hodgon on line site.
Hope this helps a little with your decision. I should get commision from Dillon, I have influenced MANY purchasers here.