what is best magnification for 250-350 yard shot?

All the optical quality magnification you can handle and afford for target shooting.

Exactly. Personally I like to be able to see bullet holes out to 300 so, depending on caliber, I look for a max of at least 30 and preferably higher so long as clarity isn't compromised.
 
For out to 350 yards,on deer or moose, you don't need a great deal of magnification. I find a 3-9x scope adequate for 500 yard shots on big game.
 
Get a high quality fixed 4 power.

You will appreciate good glass and a proper reticle way more than poor glass with higher magnification.

There is no issues with hitting the rams at 500 meters with a fixed 4 so deer/moose out to 350 will be no problem.
 
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