A lot will say Glock, and they may be right. In the end, it should be what you are most comfortable with, and what is within the budget you are willing to spend. I am relatively new to handguns and my first 2 aren't exactly the most practical for a lot competitive target shooting as one is a .50 mag and the other is a .22 mag. When I did start looking at a handgun, I had some personal criteria, and part of that was balance and feel. I ended up settling on a Sig Sauer P226. It feels great, it shoots great and it is a full metal construction, so no polymer in any parts like you will find with a lot of handguns. Not that there is any major issues with polymer as some swear by it, and my .22 mag is nearly entirely polymer.
For me, the P226 grips well, it feels well, it feels well balanced in my hand, and I feel comfortable with it bringing it up from holster into a fully sighted position. It doesn't feel too light and it doesn't feel too heavy to me. The flip side is that this is not a cheap handgun. You might find yourself looking elsewhere if price is an issue, but if it isn't, I highly recommend the P226.
The one catch you may find with the P226 is the lack of safety. Like a double action revolver, this handgun relies on a heavy 10 lbs trigger pull as it's primary safety, and will have a decocking lever to safely bring the hammer down. There is the DAK model that is double action only with a 6 lbs pull. This double action first pull can cause some issues if you decide to use it for competitive shooting as the first shot is always going to be a long travel with heavy pull, and subsequent follow up shots will have short reset (even shorter with the TacOps model) and a 3 to 4 lbs trigger pull, so it may take a bit to get the hang of it. This is where some may look at other firearms like the CZ shadow.
At the very least, the P226 is worth a consideration.