Check out my post of my whitetail buck in the "show your 2013 whitetails" thread. 364yds on the rangefinder. Only one single shot. Destroyed one lung, half the other, exit completely blew out the off-side shoulder and some brisket. Not a hard shot at all.
Dogleg, would that be an Ontario gopher? Because a Richardson ground squirrel out here might take me a couple of shots at 300+yds with my existing equip. Although, I would be close enough to stun it with shrapnel, but an inch is a miss with those. Usually by the end of gopher season, there is no problem hitting them with a .22 at 125yds. That's when I open up the big guns if I can. Shooting ground squirrels at 250-300yds with a .308 or an '06 means hitting anything you WANT with that rifle whenever you want. Nothing like reactive targets to make you learn to aim small, miss small...