I have gone up to 168gr in 7-08.
With various powders and charges and extensive testing I found in my 1 in 9 barrel that the most efficient bullets are 150's.This gave me the best accuracy that I could find.
I use Swift Sc II's for hunting , they were most accurate at 2789 ft/sec, with best results just touching on 5 shot 1/2 MOA groups(if I can do it) for moderate ranges , velocities maxed at 2855 with these bullets.
My target bullets are 150 SMK's , moving just a touch over 2800 ft/sec. and better accuracy than the Swift offerings.
I had 168's moving from 2500 to 2750 ft/sec but didn't get the accuracy I wanted out of the 9 twist barrel.However this was still good accuracy, just not the best.
When I loaded for 1 in 9.25" factory barrels I found that various 140's going 2800-2900 ft/sec were best for accuracy with decent velocity.
A quality 140 grain bullet moving at over 2800 ft/sec won't have any issues with getting game in Canada.
Not sure what your intended use is but there are various options but I would venture that for hunting or target you best results in a factory twist will be the 140's and possibly the 150's using a powder as H4350 or something similar.
There are however so many variables that will come into play that your rifle may like sometime different, but I would guess that for factory twist rates you may not be able to keep the bullets stable that are getting over the 168gr weight.