In order to avoid potentially specious generalization, it is possible to compare the wind drift of different rimfire rounds and their ballistic coefficients more precisely.
Here is a chart that compares wind drift for the more commonly used rimfire rounds. It is the same chart that has been in the sticky above since 2006.
The ammo that has the most wind deflection is HV 22LR ammo. The ammo that has the least wind deflection is 17HMR, followed by standard velocity 22LR despite its much longer time of flight and exposure to the wind. The explanation for these results has to do with the ballistic coefficient (BC) of the various ammos.
The BC of a bullet is essentially a measurement of how streamlined a bullet is, how well it flies through the air. It is a measurement that reflects how much air drag a bullet has. The higher the BC the better the bullet flies through the air. The BC of a bullet is derived from the bullet's sectional density (SD), which in turn is the relationship between the bullet's weight and diameter. BC can change with bullet shape and velocity; SD remains the same for bullets of the same weight and caliber.
The BC of the 17HMR, regardless of whether the bullet is 15.5, 17, or 20 grains, is invariably higher than the majority of the .22WMR ammos shown. This goes far to explain why the 17HMR experiences less wind drift than the 22 magnum round. The factor helping the SV 22LR perform so well in the wind is its relatively high ballistic coefficient.
Here are the ballistic coefficients of various rimfire rounds, of different weights and velocities.
17HMR
22WMR
22LR (for purposes of comparison)
