22-243
played with one briefly a few years ago, slow powders and long barrels are best. If your 22-250 shoots well so will the 22-243 likely. Don't bother if your 22-250 is less than 26". I went to a 28" 22-284 with a 1-8" twist, still playing but looks like a super velocity tack driver with 80-90 gn match bullets. Probably burn the throat out before I decide on a load, welcome to wildcatting !!