The overbore index of the 22-250 is high. It has a short accurate barrel life. As Richard said,
1200-1500 ACCURATE rounds, but then my definition of accurate will be different from yours. You will still be plinkin' gophers long after its prime accuracy has diminished, because you don't need quarter minute accuracy for gophers.
The 22-250 AI has an insanely high OBI and it will have prime accuracy for well under 1000 rounds
There is really no discernible difference between Chromoly 41XX and stainless 41X steels in terms of barrel life. CM has better heat dissipating properties, but accuracy and barrel life are essentially the same.