Seems H380 is available at decent prices, so will give it a try until I can find some 4895. Might even try some Big Game as will be testing it in my 30/06.
444, I can understand your wanting to experiment with different loads, it's a great way to get experience and hands on, real time information.
However, I have yet to see a 22-250, one of my favorite cartridges, not shooting well with H380 or 4895.
There may be a very slight difference in velocities, 25-50 fps when using Standard Large Rifle primers, however, if you use Magnum LRPs, that difference gets smaller, and usually the groups are identical.
When I run into this situation, I always opt for the ball powders over the extruded types. It's just another minor irritant eliminated with the powder measure when loading large quantities.
Both powders you opt for are very versatile in their usefulness across a wide spectrum of cartridges because they give acceptable results within that spectrum.
These are trying times to become a hand loader. Shortages and incredible inflationary costs have put a crimp into many people getting involved.
It's not just hand loaders that are noticing the financial crunch.
Factory-loaded ammo prices have gone through the roof as well.
I'm hearing more and more people state "I just can't afford to shoot as much as I would like and am considering getting out"
Most of them just put their firearms away and hope prices for components or ammunition will become more affordable in the near future.
IMHO, they're going to have a long wait.
There are several hot spots all over the world happening at the same time and they have been ongoing for the past 3-4 years.
Government contracts come first. Anything left over will be very limited and the manufacturers will charge what the markets will bear.
I don't see this situation alleviating anytime soon.
Whichever powder you settle on, don't just purchase one pound, if you can afford more. Same goes for Food Court shops.
Check the lot numbers on your powder canisters, if they're different, blend them, to make one consistent lot.
DO NOT BLEND POWDERS WITH DIFFERENT DESIGNATIONS TOGETHER.
Even when powders have identical burn rates, the volumetric differences can make for nasty surprises.