It's like a .22lr on steroids, and I regret selling mine. It dropped hefty groundhogs with authority (the .17HMR does not), and was plenty accurate out to 100 yards for that. I wouldn't take it out coyote hunting, but wouldn't hesitate to shoot one inside of 75-100 yards if the opportunity presented itself. As for game size, anything up to and including groundhogs/foxes I'd say it's a great caliber, but with that extra power comes allot more noise too. I tried 9 varieties of .22WMR ammo through my Savage and couldn't reliably get it to shoot MOA with any of them. Sure, lucked into a couple of groups that did (Hornady 30gr. V-Max) but most groups were in the 1"-1-1/4" range. Because I consider it a closer-range gun, mine wore a 3-9x40 AO scope, and I found that to be sufficient. Another .22WMR is on the radar for me in the next year or so, toying with the idea of getting a Ruger American. I've read good things about that rifle, in that caliber.