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Unless your .243 is going to be permanently set up for varmints, then your deer bullet will probably do. I hate having to re-sight my gun in when changing bullet weights.
I use 75 gr V.MAX for yotes, I also was yote hunting this year and. 4pt Buck came out late season. I took him with this bullet at 185 yards, Deer went 20 yards in the tree line and piled up.