For moderate range deer hunting, the 243 will work just fine. There's a few real good factory ammo options for deer such as 85 grain Federal TSX, 100 gr Federal Nosler Partitions, Winchester Supreme 95 grain Xp3. Alot of good options for varmint loads too, ranging from 55 grain to 85 (I count eleven from Federal, Remington, Winchester, & Hornady). There is no doubt the 25-06 is a superior deer and larger game cartridge, but inside 150 yards, it just doesnt take THAT much power to kill a deer, assuming the bullet can be placed in the right spot. Much less factory ammo varmint weight options for 25-06, I count
three! (Winchester 85 gr BST, 90 gr PEP, & Federal 85 gr NBT). 243 Wins hands down
Ive owned two 243s, and have yet to own a 25-06. I did however own its short action ballistic twin, the 25-284, which I enjoyed. I sold it because it simply did not do anything my 260 Remington doesnt, except burn 10 grains more powder. But since we're talking factory ammo here, there aint much point in going further
243