Bullet inflicted damage to game is a function of construction, impact velocity, and bullet placement. If the bullet expands to .60" the shank diameter has little to do with the wound volume. GS Custom in RSA is a maker of mono-metal bullets similar to the Barnes TSX, and they have pics of game shot with a 45 gr .224 bullet from a cartridge that is essentially a .22/06 with a MV of nearly 5000 fps. They claim the game drops as if hit by lightning with less meat damage than the same game shot with 100 gr .243's. Me being a fancier of heavy for caliber bullets at moderate velocity, sees that a brave new world in bullet performance could be emerging.
I think the one factor that needs to be stressed, however, is how much metal the bullet sheds as it travels through the animal. Bullets with low weight retention cause extensive damage to meat with fragments traveling up to 18" from the wound channel.
There are basically two types of meat damage......one from that actual shock of impact and the other from foreign particles traveling through the meat, so a rapid expansion bullet or even an old favourite like the Core Lokt can do far more meat damage traveling at a realatively low speed when compared to a bullet like the TSX going at high speed.
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