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Yes indeed, but popular wisdom will tell you to back off a bit on the load and work back up, as you should do whenever you change a component in a given load.
You might find you have to adjust OAL slightly when loading JSPs using JHP loads (HPs are usually longer than their same-weight SP counterparts because of the cavity).
I find the 125gr. is a bit flatter shooting out to 100yrds, but I haven't used a lot of them, so I'm no expert. I mainly use 158gr. Lots of loads for both .357 and .38 spl.
They just have different applications, which doesn't really apply in Canada.
I was reading in the Speer manual just yesterday how the hollow-point 158gr. are great for hunting small deer species, and the 125gr. hollow-points are ideal for self-defense purposes.
Not sure that i understand this, the same load with a lead bullet(of the same weight) will produce less pressure and should be safer. In most handguns, lead bullets can be loaded to exceed the vel. and energy of jacketed bullets due to lower pressures. Just this weekend I was testing cast bullets at close to 2500fps in my Marlin, with loads I wouldn't try with jacketed. When I happen on ammo with jacketed bullets, I usually either use them for cheap range practise or pull the bullet and load them up with heavy cast bullet loads. This of course pertains to handgun or big bore rifles.