I have both a .357 and a .44 on my ATC. I should drop the .357 and get a second .44 or a .45. My .44 load is 20 gr of H-110 under a 325 gr WFN hard cast bullet from MT Chambers, which clocks about 1200 fps from a 5" barrel. My .357 load is 13.0 grs of H-110 under a hard cast 190 gr SWC for about 1150 fps from a 6" barrel. The penetration with both loads is similar, but I think the edge goes to the .44, and for overall terminal performance on a live target, the .44 has it all over the .357. Of course if your target is a bear approaching head on, the only shot that will work is the very tricky brain shot, that will be equally effective with either bullet. If you get it right the bear is rugged, if you don't, well we don't even want to consider what might happen then. The reason the shot is tricky is because the brain pan is only the width of the snout, so the massively wide head, which is in motion, unless he's focused on you, confuses the aiming point, and the close range of the action might cause you to shoot low.