Remember it isn't about YOU or even SELLING the thing; it's decades down the road. If your kid or grandchild (or anyone for that matter) should drop a factory .357 mag round in there (or whatever) that YOU 65 years ago knew to handload down, well... it's your own personal ethical decision there.
Kinda like selling a used car without having it governed to 50 kmh...after all some future doughhead might step on the gas in a school zone or something like that....
I'm currently working (cutting to octagon) on a 4140 CM 45-70 barrel for a # 1 Rem RB action and have complete confidence in doing that as I never intend to exceed BP pressures. As for a FP block coming unhooked, I have studied the RB for some time and altho Tiriac has seen photo's of this happening I never have. I have seen a # of photo's of RB that have split at the top ring causing. This allows the sidewalls to separate as well, allowing the pins to be turned loose at on end but every photo I have seen and altho they are disoriented, the blocks are still on the pins. Virtually every photo that I can remember seeing of a destroyed RB was a re-barreled BP # 1 action that had been converted to a modern high pressure smokeless powder chambering. Some people don't realize that there is a very big difference in metallurgy from the Swede's, Danes and milt #1 1/2 smokeless actions to the #1 BP action.
Agreed that .38 special with a good barrel marking is fine for something like this; .32-20 would be neat. .44 -40 as someone else suggested ought to be a decent idea also, without seeing it in person. Backthrust is probably the key consideration although a brittle cast iron receiver would certainly make me think it through carefully.
Good luck OP it has a great potential to be fun rifle regardless.