Loading the Marlin up to the maximum can be tricky. There are normaly 3 differnt levels for the 45-70. #1 Trap door, #2 Marlin, #3Ruger. This part is straight forward, get a loading manual and follow the Marlin loads. The tricky part is that many handloaders load the MODREN Marlin to a level between the normal Marlin listing and the ruger listing. So infact ther are actualy 4 differnet loading levels.
Marlin only recomends the 35,000cup loads for the 45-70 HOWEVER is is common practice to load the Marlin up to 43,000psi. This is equal pressure and preformance to the 450 Marlin.
If you are going to hot rod the 45-70 in the Marlin you realy need a cronograph. Normal signs of high pressure will not show up at 43,000psi, there realy is no good way to let you know that you have gone to far. The crony is the only way.
I load the 350g Hornady out of my Guide gun with h4198 to a velocity of 1900fps. I have used R7 and 400g bullets but cannot remember the loads and safe velocitys off the top of my head.
Be carfull following someones loads on the internet, I have found a BIG difference in case capacity between Remington and Winchester brass, if you were to use a powder charge that was safe with the Winchester brass you would be over the pressure limit with the Remigton brass due to it's smaller capacity.