45 long colt or 610 10 mm

I would strongly suggest going with the 610. You can use .40 ammo and if you want more pop 10mm is pretty potent. Depending on the load and gun .45Colt can be loaded to perform similar to .44 Mag.
 
Check around to see which one has ammo/acomponents more readily available. Out here, neither one is easy to find and if u do find some, it will cost you dearly.
dB
 
Check around to see which one has ammo/acomponents more readily available. Out here, neither one is easy to find and if u do find some, it will cost you dearly.
dB

If you are talking strictly loaded ammo sure. Otherwise with access to good shops or the internet both should be reasonable. .40 and .452 projectiles and suitable powders/primers can be found at any decent gunshop. The only other issue is brass which is only an issue once if you buy enough.
 
"...which round is more powerful..." Not that it matters much but the Colt can use 300 grain bullets at around 700 + fps. The S&W up to around 200's at 810fps. However, if you're not reloading yet, the S&W is a fair bit less expensive. Around $30 per 50 vs nearly $50. It's comparing apples and oranges though.
Finding an S&W in .45 Colt might be an issue too. Not impossible, of course.
 
If you handload the 45 Colt is the more powerful round. This is why revolvers are generally used for hunting rather then semi autos. Yes, there are exceptions, but not many. Keep in mind that you can't use the most powerful 45 Colt ammo in S&W, they aren't strong enough. If you want to push the 45 Colt harder, you'll need a Ruger or Contender. FWIW - dan
 
Go to this link and look at the reloading data. This is your best way to answer this question for yourself.

http://data.hodgdon.com/main_menu.asp

Neither 10mm ammo or brass are easy to find. But .45Colt brass is pretty good since it's a common cowboy action cartridge. But because the focus is on cowboy action shooting with .45Colt you'll find that much of the commercial ammo is toned down in power. To get the power at the limit that the cartridge is rated for you'll pretty much need to reload.
 
Neither 10mm ammo or brass are easy to find. .

I'd argue the opposite. I have ridiculous amounts of virgin and fired brass. I have no trouble finding it. Loaded ammo is different but really, if you buy any 10mm with the intention of shooting factory ammo you need to think a little harder about your purchases... If the OP could produce more info about what he wants I am sure we could be a bit more helpful...
 
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