A .449" bore size is technically correct, since the bore size before rifling (according to the sealed pattern) was supposed to be .441". The depth of the rifling was stated to be .004" according to Bruce & Reinharts book on the Webley Revolver. So 2x.008" plus .441" = .449". If you account for manufacturing tolerances and bore wear, anywhere from .449"-.452" or possibly even larger, is within the realm of possibility. The mk1 I had measured .4495", while both my current Mk2's measure .451" and .4515" respectively. OTOH, my "WG" in .476" slugs out at a whopping .466".
For loads, I have used 5gr of Unique with a 250gr flatpoint "cowboy" bullet with great results. I have also used 5.8grs of Blue Dot with equal effect. Both of these powders work best in the shorter mk2 case currently available from Hornady and Fiochi. I have also used Blue Dot in the longer Mk1 case, although I had to bump up the charge weight. The original Black Powder load, which used the mk1 case, produced a velocity of 700fps with the 265gr hollow base bullet. The smokeless load using the shorter mk2 case produced 600fps with the same bullet. It's best not to hot rod these old guns. If you can develop a load around 600-650 fps with a 250gr lead bullet that shoots around 4" groups I'd call it good. Accuracy brings up another point. Many of these old Webley's didn't have the most accurate Crown job when new, and 100+ years of knocking around didn't help them get any better. Have a gunsmith check and touch up your revolver's crown if necessary, it really makes a difference.