Just got back from the range and had some fairly decent results with the RL 25 and IMR 4350.
RL 22 was the least impressive, velocity wise. Started with 51 gr and went up to 53 (book max) in .5gr increments. 51 gr produced 2751 fps and 53gr was 2858 fps.
With the RL 25, I started at 51gr (2728 fps) and worked up to 56.5 for 3045fps. Managed to shoot a 5/8" 3-shot group with the top load, which made me quite happy!!
Probably the most surprising (to me, anyway) was the IMR 4350. Just for fun (I honestly wasn't expecting great results), I loaded 5 rounds from 48 gr to 50 gr (.5gr over book max) to try out. 48gr produced 2900fps and 50gr was 3008fps. The surprising part was that all 5 shots produced a 1 1/8" group. Will definately be doing some more work with this powder.
No pressure signs whatsoever with any of the rounds. All of the primers looked good, and extraction was not an issue at all. I'm quite happy with the velocities, but will see if I can improve on them a little with the 4350 and RL 25.