Yes, it removes, without taking the side plates or grips off.
--Open cylendar, (Unloaded of course!)
--Insert a small pin (thumb tack, earring, safety pin) through the tiny hole in the side of the frame. Hole is on the thumb side of the frame, if you are right handed, under the cyl, near the front of the frame.
--Remove the screw from the front of the frame, that faces rear-ward towards the back strap
--The pin you put in keeps the nut from turning inside the frame.
--With screw removed, the crane and cylendar will fall off.
--The cylendar (With ejector) just pulls off the crane, for cleaning the axle, etc.
I've never bothered taking the ejector assembly out, Not sure if it is right of left handed threads, and there's enough S&W's out there that people have put the pliers to, so I just spray the ejector out really well, and let it run.
I always meant to use White lithium grease for the axle to cylinder surface, but I never had any on hand, so mine just runs on Balistol.
Re-assembly is the opposite of disassembly. Just the pin in critical, otherwise the nut the screw thread into just spins, and will never tighten or loosen.
6700 rounds and counting!