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The .22 rimfire cartridges, because of their small size and capacity, are loaded with very small shot, usually #11 or #12 shot, NOT BBs. As mentioned, some leading MAY occur so clean your rifle after using them. They were designed for very close ranges at things like Sparrows inside a barn.
Because of the rifling, they do tend to give "donut" types of patterns because the rifling spins the shot. Regular "Skeet" targets are fairly hard and thick to withstand the launching of them by machines, and with very small shot, I can see that they would not be broken. However, at one time, Mossberg made a smooth bore rifle that had a spring loaded launcher attached to the barrel, and used miniature "Skeet" targets. It was called the Mo-Skeet-O. Remington also made smooth bore rifles for shot shells, and also some rifles that had a few inches of rifling, then a smooth bore in the barrel so you could shoot regular .22 RF with some semblance of accuracy.
Generally, most people who use them are disappointed with the results, as they are used to regular shotgun performance and the .22 RF shot shells are way behind even the .410.
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