At ranges long enough that MOA accuracy matters when shooting at big game, so too does a higher BC become beneficial. BC doesn't matter from the viewpoint that vertical trajectory is predictable, under similar conditions is repeatable, and is easily compensated for by a few clicks on the elevation turret, or by holding a touch high or low. But attempting to compensate for gusty winds is another matter entirely; a high BC bullet that is less prone to wind drift is arguably superior to one that mimics a leaf. In windy conditions the advantage of high BC is observable and is easily proven. Then consider a situation where wind becomes a component of drop, such as a high wind blowing down the side of a mountain; if there was any shot at all, I wouldn't be looking for a round nose bullet to use in that scenario. The idea that high muzzle velocity can makes up for BC might well have validity due the bullet's reduced flight time across typical hunting ranges. That said, it reminds me of the guy who told me that his 7mm Remington Magnum was so fast he didn't have to lead running game; I suppose he was right if the game was running directly away. Likewise, to announce that high velocity negates all advantages of a high BC bullet . . . I suppose you might find a scenario where it applies.