I've messed with a lot of calibers and a lot of coyotes. Best all around bullet for saving fur was the 62gr Berger FB Match, although those are now discontinued i believe. 2nd best would be the 70gr Nosler Varmageddons (not the BT Varmint), neither of which pushed at extreme speeds.
If you're strictly looking at knock down, 70gr blitz king, 70gr-90gr vmax, even those new ELD Varmint bullets from hornady would work well. Judy find an accuracy node, work a load and run with them. If saving fur isn't important, push them fast and hard and you'll be successful!