Best powder for these calibers

Varget can potentially fill the cases of all those cartridges. I use 36 grains in my 22-250 with a 52 gr FB varmint bullet, and I use 45 gr with a 175 SMK in my .308. I know my shooting partner uses Varget with his 80 gr bullets in his .243 as well. It's an awesome powder to start with, very temp. Stable and may fill your needs. As always, your guns will dictate what they like.
 
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