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A full size Sig like a P220 or P226 would be my recommendation. But I am quite biased. The M&P's can have a pretty big backstrap put on I believe, and a Beretta 92 fills the hand quite nicely as well.
Reliablity: With full loads, yes.
Accuracy: Yes
aftermarket parts: What are you looking for?... But it does come in a plethora of finish...
Cost/value: The smile per/$ is pretty good...
Not a 1911 frame: Nope...