I had a plain 4-12 trophy on a M70 coyote in 22-250 that I use to have, and it worked great, shots from 30 to 500y and it was always right on.
As of now I have a 3-9x40 DOA 250 on my Encore ML LOVE this scope. The dots are set for a 250gr sabot and 150gr powder and should get you to 250y.
I shoot 300gr and 100gr of powder 100y=0", first dot 125y=+1.5", second dot 150y=0", third dot 200y=+1". So the DOA works great for me, scope is nice and clear, all adjustments work awsome. I've always have liked the trophy scopes and have had a couple that have always worked great never a problem, I think the scope is even better now with the new design and the BC scope covers, I'ed buy another one and probably will.
I know it's not a 4-12 doa 600 but I hope it helps.