My experience with these bullets was less than stellar. I have been trying to load them in a 629 and except when using the softest loads possible, I have been having extreme leading issues. The bullets are 240 grain .429, and I must say that the lube is hit and miss.
For comparison, I tried some 240 grain .429 from OMA Products on Vancouver Island (as far as I can tell they are using the exact same mould) with the exact same powder, load, etc. and had a LOT less leading then the Cactus Plains, and the lube was way better.
Now having said that, a number of friends are using the Cactus Plains in their semi-auto pistols without an issue, and one fellow loads for his 44-40 without significant leading, so who knows (though they all complain about the hit and miss lube).
Just my experience.