Just to stir it up, do you think she may want to shoot larger species? Moose perhaps, yes 243 can do it if the right bullet is placed in the right spot.
Someone mentioned the Rem model7 I would tend to agree with that, they are light enough that someone of limited upper body strength will be able to handle, and they are good shooters. I would opt for the 260 simply for the bigger bullets and more options in bullets. Now if they made it in 257 Roberts, that is what I would do,, but they don't offer it from factory, hence I make my own.
The 260 has light recoil and with the 140 grain bullets will have better retained downrange energy and less wind drift to deal with.
6.5 x55 or 7x57 or 7mm08 all are other good choices, but most are only available in full sized rifles and if the rifle does not fit her or she can't support it, will she shoot it?? :mrgreen: