Late to the party, but I also have a Henry Big Boy in 45 Colt and shoot Campro projectiles. I have only tried a few loads but based on my research Lyman is one of the few manuals to list 45 Colt rifle loads. The firearm Lyman used is a Winchester Model 94AE with 16" barrel.
For 250gr projectiles, they list Titegroup, W231, AA#5, Unique, Power Pistol, N340, 2400, IMR 4227, and 5744.
I tried Unique, Power Pistol, and 2400, and the best groups by far were with the Power Pistol. But... even at 100 yards, my group size is at least 4" (3-9X scope). Unique was very dirty and not accurate. 2400 was "clean" but 6-8" groups easily.
Lyman has the fastest load being 2400 (at 1236 ft/s) followed by AA#5 (at 1217 ft/s). OAL of 1.59"
With your powders (the only one listed was IMR 4227) they list 17.0 gr - 20.3 gr (WARNING! DO NOT USE - VERIFY) for velocities of 949 ft/s - 1198 ft/s/.