Can I assume all P320 full size holster will work with P250 as well?

I’m pretty sure the answer is yes...the only difference between them is the dao on the p250...frame and slide are effectively the same sizes...
 
Yes they'll fit.

The only time I imagine there being an issue is if you got something like a Safariland with a hood, DAO hammers leave some wiggle space.
 
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