I have to say, it would make one hell of a practical joke. I always wanted to load a round or two of 9mm with some holy black and switch it out on an unsuspecting victim.

Then be there to laugh and clean my mess up like a responsible prankster.
Never tried it, but even the 30-30 has too much overbore for black powder. And I have bandied around the idea of stuffing mine full of FFFg. .303 British was originally a BP case, and I've known some guys to have not bad luck with it iin that capacity. The .303 used a solid black powder pellet with a hollow in the middle (sound familiar?) that was inserted into an unformed case, the neck and shoulder were formed around it. Much like the cordite load.
The .300 Mangle-um on the other hand. Well you might get one round down the pipe, but the bore might be plugged solid with fouling. Don't worry, there would be good gas seal. All of my BPC stuff (.45-70, .45-90, .44-40, .44 Russian, .32 MH, etc...) all looks shiny new on the outside after firing. Encrusted with filth on the inside.
I'd definitely wipe between shots. No room for blow tubing there.
In short... from this point forward, take all stories from this guy with a BIG grain of salt.