Can't speak for the H&K but I shoot them out of polygonal rifling once in a while. And it's a Desert Chicken, so I have it twice as bad with the gas system to worry about. I don't shoot this gun very often but haven't had any trouble with the few cast I have shot out of it. I check the barrel for lead fouling and then blow out the gas system (a la AR) with a few copper plated rounds. Take home and clean with brake cleaner.
If you are going to be shooting lots of lead out of this gun frequently, I'd keep an eye on things just to make sure you get no leading and if cast shoots with the same accuracy as jacketed or plated. You might just be lucky enough to use them often.
If you are casting your own, you can fine tune with sizing dies, loads and different lubes since they all have an affect on degrees of leading (or better put... lack thereof) out of any barrel.