I have a 625 & Anaconda in .45 rather than .44.
Anaconda is a larger & stronger gun than the S&W, more on the scale of the Redhawk.
If you are planning to fire large quantaties of .44 mag, I would track down a 5-1/2" Redhawk rather than either Colt or S&W.
If you are looking for collector "cachet" with limited heavier loads, go with the Anaconda.
If you are going for a "packin' pistol" go with the Smith.
The Colt is a larger & stronger frame & cylinder, while the S&W has better lock work. One of those 6 to 1/2 dozen deals...