I really like the idea of having a calibre that you can hunt big game with if you so choose. The 243 won't damage pelts with the right size lead so this would make my choice very easy. I have seen a lynx go down to a 7-08 and not have an exit so The idea of reloading would be factor. If you are going to, then big caliber, small bullet. If you want to shoot cheap 223, and buy ammo by the 200 round lots. Of course I say this and then went and bought a 22-243 middlestead. " hypocritical??" But most of my yote hunting is done with a 25-06 and 75gr v-max. Just my 2 cents