Africa
It's getting harder and harder to travel with firearms, last fall we were only allowed 5 Kgs of ammo and must be in a locking metal box. (airline rules). So you have to be real conservative on ammo, having said that, in a mixed bag hunt of plains game and big game 2 rifles is best.
I like a .300 for general hunting and have taken everthing up to Eland flawlessly with 200 gn A-frame and / or TSX. This will be your constant companion for everything from Stienbuck and Duiker to Eland and Roan and very likely leopard, croc and even lion depending on your PH and hunting style. For this gun you are going to want lots of ammo 100 rds min.
Then your heavy .416 and up for Buff, Rhino and Eles also carried when tracking in heavy bush for smaller stuff. For this rifle I like 50 rds but 20-30 is probably lots in reality.
I have taken a shotgun twice and had a blast but that was before ammo restictions. These you can usually rent there and buy the shells there. If you are a birder at all, take a couple of days for birds cause it really is fun, all the doves you can hammer and sand grouse, if you think you're real good with a shotgun these birds will give your ego a reality check.
This is some of the most fun of an African hunt is the planning. One more word of advice, plan your hunt, make your budget, add a little for incidentals and then DOUBLE it. There are always opportunities that pop up when you're there like a second buff or a cull or second Ele or an animal that isn't common to the region pops out and you can have it. Sometimes a bordering concession has a strike out on a buff or Ele or lion and you get the opportunity to add this to your bag.
I could go on "ad nauseum" but I won't
Douglas